Mutagenicity of Chinese traditional medicine Semen Armeniacae amarum by two modified Ames tests

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Mutagenicity of Chinese traditional medicine Semen Armeniacae amarum by two modified Ames tests

BACKGROUND Semen armeniacae amarum (SAA) is a Chinese traditional medicine and has long been used to control acute lower respiratory tract infection and asthma, as a result of its expectorant and antiasthmatic activities. However, its mutagenicity in vitro and in vivo has not yet been reported. The Ames test for mutagenicity is used worldwide. The histidine contained in biological samples can i...

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Modifications of Ames Test for Assessing the Mutagenicity of Traditional Chinese Medicines

Traditional Chinese Medicines (TCM) are histidine-containing biological samples, they are commonly orally taken in the form of water extracts. False-positive results of TCMs’ water extracts may get when using standard Ames test, therefore the interference resulted from histidine within the samples must be eliminated or reduced, and the standard Ames test needs to be modified. This mini-review s...

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ژورنال

عنوان ژورنال: BMC Complementary and Alternative Medicine

سال: 2009

ISSN: 1472-6882

DOI: 10.1186/1472-6882-9-43